There is evidence that through the Transcendental Meditation (TM) method it is possible to obtain changes, especially in the physiology of individuals (R.K.Wallace).
All these changes imply a distinguishable physiological state and that we can define as a hypometabolic state, which causes deep relaxation, but in a mental state of wakefulness and alertness (R.K. Wallace, H. Benson and A.F. Wilson).
A state of greater stability of the Autonomic Nervous System would also be achieved (d.W. Orme-Johnson).